AEROSIL® 200 Pharma (Antwerp)
- INCI/Chemical Name:
- Colloidal Silicon Dioxide Anhydrous USP-NF Ph.Eur BP JP IP
- SKU:
- BP130670
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AEROSIL® 200 Pharma is anhydrous colloidal silicon dioxide (also known as pyrogenic, synthetic or fumed silica) and corresponds to Silica, colloidal anhydrous in the Ph.Eur, Colloidal silicon dioxide in the USP-NF and Light anhydrous silicic acid in the JP. It is obtained synthetically from silicon tetrachloride at high temperatures.
AEROSIL® 200 Pharma is supplied as a white, light, fluffy and extremely fine powder. The primary particles are nanosized, however, they readily agglomerate such that the average particle size of this grade is about 50µm. It is a widely used excipient, stabiliser and additive in pharmaceuticals, cosmetics, and food products.
Features
Synthetic, high purity and excipient grade raw material
Global approval for pharmaceutical and food use (Ph.Eur, USP/NF, JP and IP. Meets purity criteria of E551 according to 231/2012 EU)
Excellent glidant for tablet, capsules and powder formulations
Stabilises oils and emulsions
Specific surface area 200 m2/g
Benefits
Absorbs/binds moisture which can be advantageous in moisture-sensitive formulations
Small particle size and large specific surface area is advantageous as a flow aid for dry powders in tabletting and capsule filling
Improves tablet hardness during compaction
Excellent flow characteristics in powders
Can be used to make transparent gels
No influence on taste and does not alter the natural colour of powder formulations
Applications
AEROSIL® 200 Pharma is widely used in pharmaceuticals, cosmetics, and food products as an anticaking agent, emulsion stabilizer, glidant, suspending agent and viscosity-increasing agent
In topical aerosols AEROSIL® 200 Pharma promotes particulate suspension, eliminates hard settling and minimizes clogging of spray nozzles
AEROSIL® 200 Pharma is also used as a dispersing agent for liquids in powders
AEROSIL® 200 Pharma is added to suppository formulations containing lipophilic excipients to increase viscosity, prevent sedimentation during moulding and decrease the release rate