Crospovidone XL (EP)
- INCI/Chemical Name:
- Crospovidone Type A Ph. Eur
- SKU:
- BP141054
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Crospovidone is a synthetic polyvinylpyrrolidone polymer obtained by polymerisation of vinyl vinylpyrrolidone. It is insoluble in water but swells due to pronounced capillary activity and hydration. The exact molecular weight of Crospovidone has not been established due to the material’s insolubility.
Copovidone is official in all the major pharmacopoeia and is approved for use as an excipient and additive. Crospovidone from JH Nanhang is supplied as a creamy-white and is available in three grades of fineness: standard, fine and micronized.
Features and Benefits
Crospovidone XL has a particle size of 40 – 120 µm, corresponding to Type A in the Ph.Eur and BP
Compatible with a broad range of APIs
Generally regarded as non-toxic and non-irritant material. Accepted as a food additive in Europe. Listed in the FDA IIG database (oral and topical).
High swelling capacity and hydration capacity
Large particle sizes provide faster disintegration compared with small particles
Applications
Crospovidone is a water-insoluble tablet disintegrant (superdisintegrant) added to formulations at concentrations of between 2-5%.