Postbiotic Powerhouse for Health
L. Rhamnosus CRL 1505 HI: Enhancing Oral and Gut Health with Postbiotics
Postbiotics, the non-viable bacterial products or metabolic byproducts from probiotics, have gained attention for their health benefits. One such postbiotic is Lactobacillus rhamnosus CRL 1505 HI, known for its potential to improve both oral and gut health. This article explores the benefits of L. rhamnosus CRL 1505 HI and its efficacy, even with inactive cells.

What is L. Rhamnosus CRL 1505 HI?
L. rhamnosus CRL 1505 HI is a strain of Lactobacillus rhamnosus, a type of lactic acid bacteria from CSL Sacco. Unlike probiotics, which are live microorganisms, postbiotics consist of inactivated bacterial cells and their metabolites. These components can still confer health benefits without the need for live bacteria.
Benefits for Oral Health
- Reduction of Oral Pathogens: L. rhamnosus CRL 1505 HI can inhibit the growth of harmful bacteria in the oral cavity, such as Streptococcus mutans, which is a primary contributor to dental caries.
- Anti-Inflammatory Effects: The postbiotic helps reduce inflammation in the gums by promoting the production of anti-inflammatory cytokines, potentially preventing periodontal diseases.
- Enhanced Immune Response: It boosts the local immune response in the oral cavity, enhancing the body's natural defences against infections.
Benefits for Gut Health
- Gut Microbiota Balance: L. rhamnosus CRL 1505 HI helps maintain a healthy balance of gut microbiota, which is crucial for digestive health.
- Immune Modulation: The postbiotic modulates the immune system by increasing the production of anti-inflammatory cytokines and enhancing the activity of immune cells.
- Protection Against Pathogens: It provides a protective effect against intestinal pathogens, reducing the incidence of infections and promoting overall gut health
Efficacy of Inactive Cells
Even though the cells of L. rhamnosus CRL 1505 HI are inactive, they retain their beneficial properties. The heat-stable nature of these cells have been shown to have immunomodulatory activity, significantly increasing the production of specific antibodies and enhancing the immune response. This makes postbiotics a viable alternative to probiotics, especially in situations where live bacteria may not be suitable.
Postbiotics in Formulation
FORM-0005776
This innovative drinkable shot is a powerful yet refreshing oral and gut health booster. Packed with beneficial compounds, it acts first to maintain healthy gums while providing a fresh, clean feeling. It works to restore and protect the oral environment by preventing the growth of bacteria and contributing to overall gum health. This is achieved using a combination of Postbiotic CRL 1505 HI and Orophenol® an extract of polyphenolic fractions. Secondly, the post-biotics continue their work along side a soluble fibre to improve gut health. Orophenol® is a standardised water soluble functional extract of polyphenols obtained from Canadian wild blueberries, cranberries, and strawberries. Polyphenols are a family of plant metabolites involved in plant protection from oxidative stress and aggression by pathogens. The polyphenol profile varies among plants. Blueberries, cranberries, and strawberries are rich sources of polyphenols including phenolic acids, flavonoids, and procyanidins, with overlapping and complementary activities. For each of the three types of berries, Symrise with its diana foodTM portfolio has identified polyphenolic fractions capable of interfering with the growth and biofilm formation of bacteria associated with dental plaque formation and periodontal disease, such as F. nucleatum. The most efficient inhibitory fractions of each fruit were combined in Orophenol®. PROMITOR® Soluble Fibre provides health benefits including helping to maintain healthy postprandial (aftermeal) blood glucose and supporting gastrointestinal health through prebiotic effects, as well as enhancing calcium absorption, which may support bone health. The postbiotic CRL 1505 HI are non-viable cells obtained upon microbial growth and metabolic activity. In addition to general well-being, they are notable for their ability to retain many of the bioactive properties typically associated with probiotics. Viscosity, to temporarily retain the active ingredients on the gums, is achieve using NUTRAVA® Citrus Fiber zest, which is nature-based and made from sustainably sourced citrus peels, an abundant by-product of the juice industry. Typical content of dietary fibre in NUTRAVA® Citrus Fiber zest is at a minimum of 80% with an approximately balanced amount of soluble and insoluble fibre.
Clean-Label
Allergen Free
GFSI
FORM-0004760
A formulation designed to meet HFSS regulation targets with the additional benefit of nutrition claims: Source of fibre Calcium fortification Vitamin E fortification Promitor® 70H R is essential in HFSS targets to reduce sugar. It also helps to depress the freezing point to improve the mouthfeel. Sisterna® SP70 is a speciality emulsifier providing enhanced mouthfeel and added perceived whiteness. It also has the benefit of managing the ice crystals, so key to the quality of ice cream. Consider adding post biotics for enhanced immunity and digestive health.
GMO free
GFSI
Gluten Free